It has previously been demonstrated that the antiviral effect of IFITM2 and IFITM3 on infection by susceptible viruses such as IAV, can be attenuated in the presence of the amphiphilic antifungal drug amphotericin B (AmphoB; Lin et al., 2013; Wrensch et al., 2019). Here, IFITM2 is linked to infection.