This was not seen in dithizone-treated HFD mice, with significantly lower insulin levels (mean: 2.18 ± 0.36 vs. 6.63 ± 1.29 ng/ml, p = 0.0079, Figure 3C), HOMA-IR (mean: 18.31 ± 1.87 vs. 64.90 ± 8.71, p = 0.0002, Figure 3D), and glucose intolerance (mean area under curve: 2,220 ± 230.1 vs. 3,163 ± 181.0, p = 0.0323, Figures 3E,F) when compared to non-treated HFD mice. This evidence concerns the gene INS and Glucose intolerance.