In an 8 week long randomized controlled trial on 64 type 2 diabetic patients (12 were male and 52 were female; age range: 30-60 years), chamomile tea in the dose of 3 g/150 mL thrice a day showed a significant diminution in the HbA1C level by 5.01%, HOMA-IR level by 39.76%, and serum insulin level by 32.59% compared to baseline values and caused improvement in antioxidant activity (113). This evidence concerns the gene INS and type 2 diabetes mellitus.