– Ventricular function and anatomy – QRS complex width – Size and function of the left atrium – LS – Tricuspid/pulmonary valve regurgitation – Left ventricular dyssynchrony (MRI) – Increased late gadolinium enhancement of the left ventricle (MRI) – Peak VO2– VE/VCO2 slope – Heart rate response – Oxygen saturation – NT-proBNP and another biochemical parameters. Here, NPPB is linked to pulmonary valve insufficiency.