Our results in terms of inducing apoptosis by ALT and Brv-A were consistent with previously conducted studies where ALT induced apoptosis in squamous lung cancer SK-MES-1 cells (Zhao et al., 2015) as well as in A549 lung adenocarcinoma cells (Maryam et al., 2017) while Brv-A induced apoptosis in breast cancer cells (MCF-7) through generation of ROS (Saleem et al., 2020) and lung cancer cells (Khan et al., 2020). The gene discussed is GPT; the disease is lung adenocarcinoma.