Zhang et al. demonstrated that “Tiaolipiwei” acupuncture, including Zhongwan (CV12), Quchi (LI11), Hegu (LI4), Zusanli (ST36), Yinlingquan (SP9), Xuehai (SP10), Diji (SP8), Sanyinjiao (SP6), Fenglong (S40) and Taichong (LR3), significantly reduces proteinuria, improves the density of slit diaphragms, and ameliorates podocyte injury in DN rats via promoting the expressions of nephrin, CD2AP, and podocalyxin (Zhang Z. et al., 2018). Here, NPHS1 is linked to liver dysplastic nodule.