Javidanpour et al., had shown that rosmarinic acid can prevent myocardial hypertrophy, arrhythmia and cardiac dysfunction, after AMI in mice by inhibiting lipid peroxidation and overexpression of Na+/Ca2+ exchange protein 1 (Javidanpour et al., 2018). The gene discussed is SLC8A1; the disease is cardiac hypertrophy.