The expression of ALKBH1 (p = 0.036), ALYREF (p < 0.001), NOP2 (p < 0.001), NSUN2 (p < 0.001), NSUN4 (p < 0.001), NSUN5 (p < 0.001), NSUN6 (p < 0.001), NSUN7 (p = 0.006), and YBX1(p < 0.001) were significantly upregulated in tumor tissues compared with the adjacent mucosa. The gene discussed is YBX1; the disease is neoplasm.