GCH1 expression in breast invasive carcinoma (BRCA), cervica squamous cell carcinoma and endocervical adenocarcinoma (CESC), cholangiocarcinoma (CHOL), ESCA, and kidney chromophobe (KICH), kidney renal clear cell carcinoma(KIRC), kidney renal papillary cell carcinoma (KIRP), liver hepatocellular carcinoma (LIHC), pheochromocytoma and paraganglioma (PCPG), stomach adenocarcinoma (STAD), and uterine corpus endometrial carcinoma (UCEC) showed significant differences. The gene discussed is GCH1; the disease is cervical squamous cell carcinoma.