In this study, we developed a radiomics model with five independent predictors out of 851 candidate radiomic features extracted from pretreatment thoracic CT images for predicting BM within 1 year after detection of the primary tumor in patients with ALK-rearranged NSCLC, which showed a good performance with an AUC of 0.828. The gene discussed is ALK; the disease is non-small cell lung carcinoma.