According to previous studies, PTTG1 is normally viewed as an oncogene, and high expression of PTTG1 can promote tumorigenesis in many kinds of tumors such as prostate and bladder tumors (Wondergem et al., 2012; Xiang et al., 2017; Cui et al., 2020; Fraune et al., 2020). This evidence concerns the gene PTTG1 and urinary bladder neoplasm.