Patients with high expression of PTTG1 were associated with poor overall survival (OS) in ACC, KIRC, KIRP, lower grade glioma (LGG), LIHC, LUAD, mesothelioma (MESO), PAAD, THCA, and uveal melanoma (UVM) (Figure 5A, all p < 0.05). This evidence concerns the gene PTTG1 and central nervous system cancer.