In the TCGA dataset, CLDN14 expression in READ and COAD was altered by 4.876-fold and 4.368-fold, respectively, while it was altered by 3.471-fold in the dataset generated by Gaedke et al. CLDN18 expression was altered by 1.298-fold and 1.184-fold in COAD data from TCGA and Kaiser et al., and by 1.216-fold and 1.25-fold in READ samples from these two respective data sources. This evidence concerns the gene CLDN14 and colon adenocarcinoma.