The data have proven that TMPRSS2 is overexpressed in colon adenocarcinoma (COAD), cervical squamous cell carcinoma and endometrial carcinoma (CESC), kidney chromophobe (KICH), prostate adenocarcinoma (PRAD), uterine corpus endometrial carcinoma (UCEC), uterine carcinosarcoma (UCS), and rectal adenocarcinoma (READ). The gene discussed is TMPRSS2; the disease is rectum adenocarcinoma.