ATM and colorectal cancer: ATM participates in the maintenance of genomic stability and DNA damage repair (Prochazkova et al., 2015; Li et al., 2019) and has been implicated as a tumor suppressor in various cancer types including lung adenocarcinoma (Foster et al., 2019), B-cell lymphoma (Loizou et al., 2011), and colorectal cancer (Li et al., 2021).