Additionally, the TIMP1 expression level also exhibited diagnostic value for subgroups of patients with RCC as follows: T1+T2 vs. T3+T4 (AUC = 0.6414, p < 0.0001; Figure 6B), G1+G2 vs. G3+G4 (AUC = 0.6307, p < 0.0001; Figure 6C), M0 vs. M1 stage (AUC = 0.6375, p = 0.0001; Figure 6D), TNM I + II vs TNM III + IV stage (AUC = 0.6546, p < 0.0001; Figure 6E), OS good vs. OS poor (AUC = 0.6617, p < 0.0001; Figure 6F), DFS good vs DFS poor (AUC = 0.7056, p < 0.0001; Figure 6G) and male vs. female (AUC = 0.5875, p = 0.001; Figure 6H). Here, TIMP1 is linked to renal cell carcinoma.