To this end, congenic naïve (CD45.1+CD44loCD62Lhi) P14 CD8+ T cells, which specifically recognize lymphocytic choriomeningitis virus (LCMV) glycoprotein (GP) epitope H‐2Db GP33‐41 epitope, were adoptively transferred into C57BL/6 recipients (CD45.2+) engrafted with B16F10 cells expressing the LCMV GP (hereafter referred to as B16F10‐GP cells) or C57BL/6 recipients (CD45.2+) that were subsequently infected with LCMV Clone 13 (Cl13) to set up a chronic viral infection (Figure 1A). Here, CD8A is linked to viral infectious disease.