In our study, we found that virus‐specific CD8+ T cells express moderate NKG2A and NKG2A blockade limitedly enhance the anti‐viral activities of Tex cell in a mouse model of chronic viral infection, which is consistent with the fact that simian immunodeficiency virus (SIV)‐specific CD8+ T cells lack NKG2A expression.38 Here, CD8A is linked to viral infectious disease.