E2F1 and colorectal carcinoma: Previous research found that circCAMSAP1 regulated by ESRP1 could sponge miR-328-5p and then target E2F1 to mediate CRC progression (Zhou et al., 2020), and circHIPK3 could promote CRC proliferation and metastasis through the c-Myb/circHIPK3/miR-7 axis (Zeng et al., 2018).