In CRC, it was reported that peptide circPPP1R12A-73aa encoded by hsa_circ_0000423 can promote tumor pathogenesis and metastasis of CRC through the Hippo pathway (Zheng et al., 2019), and circFNDC3B-218aa encoded by circFNDC3B can regulate Snail to inhibit tumor progression and EMT in CRC (Pan et al., 2020). The gene discussed is SNAI1; the disease is neoplasm.