In order to verify whether PROX1-AS1 can influence lung cancer cells' biological behavior by targeting the expression of miR-1305 [23–25], this paper cotransfected si-PROX1-AS1 and anti-miR-1305 into lung cancer cells, and the results showed that lung cancer cells' proliferation, migration, and invasion capabilities were significantly enhanced, and the rate of cell apoptosis was significantly reduced, suggesting that lower miR-1305 expression can attenuate the influence of PROX1-AS1 knockdown expression on lung cancer proliferation, migration, invasion, and apoptosis [26, 27]. This evidence concerns the gene PROX1 and lung cancer.