Compared with the normal cognitive function group, the educational level, dry weight, extracellular water, lean tissue index, muscle mass, body mass index, albumin, and serum creatinine for the cognitive impairment group were lower, and there were fewer male patients for the cognitive impairment group, but age and fat tissue index for the group were higher, and the differences were statistically significant (P < 0.05) (Table 1). The gene discussed is ALB; the disease is Cognitive impairment.