Compared with BCMI Q2 ∼ Q4 groups, the BCMI Q1 group has fewer male patients, the highest prevalence of cognitive impairment (33.3%), higher age, dialysis age, water load, and fat tissue index, while MMSE score, predialysis BMI, postdialysis BMI, dry weight, extracellular water, lean tissue index, muscle mass, albumin, and serum creatinine were lower, the difference was statistically significant (P < 0.05), and there was no significant difference in hemoglobin among different BCMI groups (P > 0.05) (Table 2). The gene discussed is ALB; the disease is Cognitive impairment.