For example, METTL3 activates dendritic cells and initiates activation of cytotoxic T lymphocytes by increasing m6A levels of CD40, CD80, and TLR4 [26]; METTL3 overexpression promotes gastric cancer progression (GC) and liver metastasis through angiogenic and glycolytic pathways [27]. This evidence concerns the gene CD40 and gastric cancer.