Decreased levels of tumor infiltration of major immune cells (Figure 6(c)) such as CD8+ T cells (P < 0.01), macrophages (P < 0.01), Th1 cells (P < 0.001), and tumor infiltrating lymphocytes (TILs, P < 0.01), also decreased levels of immune pathways (Figure 6(d)) such as cytolytic activity (P < 0.001), inflammation-promoting (P < 0.001), and coinhibitions of T cells (P < 0.001) in the high-risk group were reported. This evidence concerns the gene CD8A and neoplasm.