In a cohort of 3,082 ischemic stroke patients, hyperglycaemic patients with higher Gal-3 levels (≥10.58 ng/mL) were found to be at greater risk of developing the primary composite outcome (death and vascular events), stroke recurrence, and vascular events only one year after a primary stroke event, with an adjusted HR of 1.72, 2.64, and 2.68, respectively, as opposed to the normoglycaemic cohort in which Gal-3 had a low prognostic value [68]. This evidence concerns the gene LGALS3 and ischemic stroke.