In addition, the receiver operating curve (ROC) analysis revealed that Gal-3 was able to predict the functional outcome of stroke at a cut-off value of 53.5, with a sensitivity of 88.4% and a specificity of 76.9% (area under the curve (AUC) = 0.884, 95% CI 0.827 to 0.941, p < 0.001), where functional outcomes were categorized into favourable and poor outcomes according to the modified Rankin scale (mRS) (mRS score of 0-2 = favourable outcome; mRS score of 3-6 = poor outcome) [46]. This evidence concerns the gene LGALS3 and Stroke.