A meta-analysis carried out calculating the standardized mean difference (SMD) and 95% confidence interval (95% CI) of cTnI or cTnT values in COVID-19 patients with or without severe disease has shown that cTnI concentration is only marginally increased in all patients with SARS-CoV-2 infection, whereby values exceeding the 99th percentile in the upper reference limit (URL) can only be observed in 8%–12% of positive cases (Lippi and Plebani, 2020c). The gene discussed is TNNI3; the disease is COVID-19.