Because high grade serous ovarian cancer (HGSOC) appears to arise in the fallopian tube from lesions that overexpress p53 protein (Corzo et al., 2017) and 96–100% of HGSOC lesions contain p53 mutations (Cancer Genome Atlas Research Network, 2011; Vang et al., 2016), this cancer was chosen for studies of the role of mortalin/p53 complexes in the SHetA2 mechanism (Ramraj et al., 2019). The gene discussed is TP53; the disease is ovarian serous adenocarcinoma.