Pathologically, the senile plaques (also known as β-amyloid plaques or neuritic plaques) and the neurofibrillary tangles (NFT) (also known as tau tangles or dystrophic neurites), observed inside and outside neurons, respectively, are two of several neuropathological features related to AD (Selkoe and Hardy, 2016; Alzheimer’sAssociation, 2020). Here, MAPT is linked to Alzheimer disease.