Finally, apart from cancer, GSDMB function has been implicated in the response to infection with Shigella enterobacteria (Hansen et al., 2021) and in the pathobiology of diverse inflammatory diseases, including asthma, inflammatory bowel disease or arthritis, among others (Li et al., 2012; Morrison et al., 2013; Söderman et al., 2015; Panganiban et al., 2018; Chen et al., 2019; Rana et al., 2022). This evidence concerns the gene GSDMB and inflammatory bowel disease.