TNFSF10 and cancer: These non-canonical TRAIL-induced pathways become visible in apoptosis-resistant tumors and by enhancing cell proliferation, migration, and invasion may lead to cancer progression (Trauzold et al., 2001; Ehrenschwender et al., 2010; von Karstedt et al., 2015; Azijli et al., 2013; Trauzold et al., 2006; Hoogwater et al., 2010).