The results of pathway enrichment suggest that the pathways involved by these genes are concentrated in Cell adhesion molecules (CAMs) (Bronikowska et al., 2021), cytokine receptor interaction (Wen et al., 2021), focal adhesion (Lu et al., 2021), NF kappa B signaling pathway (Takakura et al., 2021), proteoglycans in cancer (Jinmin Sun et al., 2021), PI3K Akt signaling pathway (Xue et al., 2021), etc, which are strongly associated with to the onset and progression of tumors. This evidence concerns the gene AKT1 and cancer.