Due to the limited sample size, the association of other cell compartments with GLILD cannot be firmly affirmed; however, a trend of lower CD19+ cell count was observed in the cases; and several authors previously stated that patients with splenomegaly, granulomas, enteropathy (33, 34), or interstitial lung disease (31, 33) had a lower B CD19+ cell compartment. This evidence concerns the gene CD19 and Granuloma.