As for the human samples, we collected the fresh tissues of ccRCC and adjacent normal renal tissues and validated the SNRPA1 in mRNA and protein levels; SNRPA1 mRNA and protein levels are significantly increased in tumor tissues as compared with adjacent normal tissues (p < 0.001, Figures 1D, E). Here, SNRPA1 is linked to nonpapillary renal cell carcinoma.