CD19 and B-cell non-Hodgkin lymphoma: In a murine model of B cell lymphoma, Chung and coworkers demonstrated a correlation between CD19 mRNA levels and the oncogene MYC expression, suggesting a role of CD19 in lymphomagenesis and arguing that CD19 ligation through targeted agents could represent a strategy to disrupt MYC signaling and interfere with oncogenesis (10).