Differences at T1D onset between remitters and non-remitters were found in terms of insulin dose (0.6 ± 0.2 vs 0.8 ± 0.1, P <0.01) and stimulated C-peptide (0.9 ± 0.8 vs 0.5 ± 0.5, P ≤0.05). This evidence concerns the gene INS and type 1 diabetes mellitus.