Several useful biomarkers, such as kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL), and monocyte chemoattractant protein-1 (MCP-1) have been identified as a predictor of acute kidney injury including TIN, however, it is difficult to distinguish TIN from other diseases with tubular injury using these markers (9, 10). This evidence concerns the gene CCL2 and acute kidney injury.