Similar to Di Bonito et al. (15), children reclassified upward by AAP 2017 in this study were more likely to be male, older, obese, and had poor metabolic factors (higher triglyceride, ALT, and uric acid; lower HDL-C; more prevalent MS) than those who remained normotensive by AAP 2017. The gene discussed is GPT; the disease is myeloid sarcoma.