Fluorescence in situ hybridization (FISH) for adult acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) identified no mutations using probes 5p15.2 (D5S23, D5S721), 5q31 (EGR1), 7cen(D7Z1), 7q31 (D7S522), 8cen (D8Z2), 11q23 (MLL), 20q12 (D20S108), and 20q13.12 (D20S150). Here, EGR1 is linked to acute myeloid leukemia.