VIM and gastric cancer: For example, Qi et al. (14) reported that the knockdown of Tspan9 in gastric cancer cells led to increases in the levels of N-cadherin, Vimentin, Twist, and ZEB1 in these cells, together with decreased E-cadherin expression, thus suggesting that Tspan9 regulated gastric cancer cell metastasis in part via modulating EMT induction.