FOXD3-AS1 is abnormally expressed in multitude diseases, including NSCLC (24–28), breast cancer (29, 30), cervical cancer (31, 32), nasopharyngeal carcinoma (33, 34), osteosarcoma (35), colon adenocarcinoma (36), melanoma (37, 38), hepatocellular carcinoma (39), thyroid cancer (40), neuroblastoma (41), glioma (42), ischemic stroke (45), myocardial ischemia (46, 47), acute respiratory distress syndrome (48), allergic rhinitis (43) and retinal infection with toxoplasma gondii-ocular toxoplasmosis (44). Here, FOXD3 is linked to hepatocellular carcinoma.