In melanoma A375, SK-MEL-1 and SK-MEL-2 cells, FOXD3-AS1 facilitates cell proliferation through binding to miR-127-3p and upregulating the expression of FJX1 (37) or by an interaction with miR-325 (38), which then increases the expression of MAP3K2. This evidence concerns the gene FOXD3 and melanoma.