ABCC6 and hepatocellular carcinoma: CCK-8 assay, colony formation assay and EdU (5-Ethynyl-2’-Deoxyuridine) incorporation assays all showed significantly enhanced proliferation ability in HCC cells with ABCC6 knockdown (Figures 4E–G), and the proliferation ability was decreased after ABCC6 overexpression (Figures 4H–J).