analyzed the protein profiles of three prostate cancer radiation-resistant cell lines (PC3, DU145, and LNCaP) and their cognate radiation sensitive cell lines using label-free liquid chromatography tandem mass spectrometry, final results revealed Aldolase, Fructose-Bisphosphate A (ALDOA) involved in the regulation of radiation sensitivity both on prostate cancer cell lines and its transplant tumor models (87). The gene discussed is ALDOA; the disease is prostate carcinoma.