collected plasma from patients with locally advanced non-small cell lung cancer treated with radical radiotherapy, proteomic analysis revealed that C-reactive protein (CRP), Lipopolysaccharide Binding Protein (LBP), and Leucine Rich Alpha-2-Glycoprotein 1 (LRG1) were significantly altered during radiotherapy, in the squamous lung cancer subgroup, both CRP and LRG1 were significantly elevated in patients with survival <17 months (22). This evidence concerns the gene CRP and non-small cell lung carcinoma.