However, despite increasing evidence that this cofactor participate in tumorigenesis and progression of various types of cancers, such as T-cell acute lymphoblastic leukaemia (34), gastric cancer (35), lung cancer (36), and prostate cancer (37), the roles of LMO (LIM-only) proteins in human glioma are unclear. Here, PDLIM5 is linked to T-cell acute lymphoblastic leukemia.