TRDMT1 and endometrial cancer: Although NSUN2 is the main methyltransferase for m5C methylation on mRNA (8, 29), we extended to explore the expression of all potential m5C methyltransferases (NOP2, NSUN3, 4, 5, 6, 7, and DNMT2) in cervical cancer, ovarian cancer, and endometrial cancer (Supplementary Figure S7).