Compared with normal breast tissue, Stat3 phosphorylation was positively expressed in the nucleocytoplasmic region of cancer cells (Figure 4E), and its relative expression showed a positive correlation with the LIF in adipocytes adjacent to breast cancer (Figure 4F), while the LIF and Stat3 phosphorylation levels in normal breast tissues were negative. The gene discussed is LIF; the disease is breast carcinoma.