In contrast to fibroadenomas, most of the breast cancers do not express DCAF8L1; Of all the 150 cases of breast invasive ductal carcinoma tissues examined, 98 (65.3%) are negative, and 31 are weak in DCAF8L1 staining; only 8(5.3%) display high expression with nuclear staining of DCAF8L1(Figure 6H). The gene discussed is DCAF8L1; the disease is breast cancer.