Analysis of data from GEPIA in BUB1 had strongly correlated with other 7 (NCAPG, CHEK, RACGAP1, SHCBP1, CDC7, DEPDC1, and TYMS) hub genes, and among them NCAPG, RACGAP1, and DEPDC1 were strongly correlated with the coefficients 0.76, 0.71, and 0.7, respectively (Pearson r > 0.5 and p < 0.1), and these expressed genes do not assume a significant part in the forecast of BAC patients yet be essential in the movement and pathology of this illness. The gene discussed is BUB1; the disease is minimally invasive lung adenocarcinoma.