We did not confirm whether our patients with CBS had these various neuropahologies based on negative results from amyloid, dopamine transporter or 18F-fluorodeoxyglucose imaging or CSF analysis and did not exclude patients with CBS who had PSP, AD, TDP-43 proteinopathy, Pick disease, and dementia with Lewy bodies pathology. The gene discussed is SLC6A3; the disease is Pick disease.