The VKORC1 variant rs7294, associated with warfarin dosage, showed a lower frequency among our central Han Chinese population (VAF = 0.0698) compared with the global populations (1KG3.ALL, VAF = 0.4197; G.ALL, VAF = 0.3948) and other East Asian populations (1KG3.EAS, VAF = 0.1121, G.EAS, VAF = 0.1013). The gene discussed is VKORC1; the disease is acute lymphoblastic leukemia.