Hypertension was not observed in non-diabetic eNOS−/−: VEGFKD mice (mean BP = 84 ± 2 mmHg vs. 78 ± 2 mmHg, + dox vs. −dox, pNS), as reported in VEGFKD mice with intact eNOS (Veron et al., 2012). Here, NOS3 is linked to Hypertension.