TET2 mutations are common in haematological neoplasms and can occur in 30% of myelodysplastic syndrome (MDS), 20% of myeloproliferative neoplasms (MPNs), 30% of secondary acute myeloid leukemia (sAML), 17% of novel AML, and 50–60% of chronic myelomonocytic leukemia (CMML) cases [16–19]. Here, TET2 is linked to hematopoietic and lymphoid cell neoplasm.