Aldh1a1 is one of the major aldehyde dehydrogenases (ALDH) responsible for the neutralisation of reactive oxygen species (ROS) that occur when cells are under nutritional and chemotherapeutic stress [22–25], and Aldh1a1 enhances chemoresistance, metastasis and tumour initiator capability [22, 26–29]. The gene discussed is ALDH1A1; the disease is neoplasm.