Using the cutoff of |logFC|> 1 and the p-value < 0.05, 13,729, 4,718, and 3,817 differentially expressed genes (DEGs) were obtained via differential expression analysis on high and low mRNAsi groups (Fig. 1A), high and low EREG-mRNAsi groups (Fig. 1B), tumor and normal groups (Fig. 1C), respectively. This evidence concerns the gene EREG and neoplasm.